Bioregulation in a system theory



In 1865 Bernard described stable internal milieu and Cannon in 1932 coined the word homeostasis. Homeostasis is the property of complex open systems, which reacts to every change, through a series of modifications of equal size and opposite direction to those that created the disturbance. The homeostatic system evolved from unicellular homeostasis via metasystem transition to the neocerebrum of brain cortex. Communication between systems remained automated in a positive or negative feedback with flow of information on a binary principle. Due to openness of the system, energy transformation and entropy fluctuation, the balance is continually disturbed and brings uncertainty of the system. Extremes of entropy states means energy dissipation or systems breakdown known as cellular death.

Bioregulatory therapy maintains maximum efficiency between systems by maintaining efficient and responsive feedback channels utilising efficient automatic control among systems. Additional corrective action is obtained by biological therapy of informational input at those levels which are rendered less responsive.
External energy input of gravitation, electromagnetic fluxes or antigens such as viruses are met by regulation of maintaining entropy by energy release (anabolism) or energy preservation (katabolism). Bioregulatory medicine maintains systems relationship by preventing extreme entropy states equivalent to tissue destruction.
Therapy is based in inducing information flow by activating resistant receptors or their cytokine mediators by Homoeopathic dilutions of biologically active molecules (hormones, cytokines, neurotransmitters) and detoxifying matrix and thus enabling cellular receptors response. At every level and their interrelationship, rules of entropy and dissipation of heat to the environment applies. System as a whole is functioning with high efficacy in cases of flexible and open communication pathways of peripheral and autonomic nerves, cytokines, hormones and membrane receptors.

Lower systems are automated with higher meta-systems of autonomic nervous system. However, the highest informational input comes from neocerebrum (mental and emotional processing), which is connected with endocrine and immune systems. The grey cortical matter is at the top of systems’ pyramidal hierarchy thus override any lower system.

Another ways of enabling system flow is by debris removal from intracellular and extracellular space, followed by stimulation of the excretory function. Excretory function restores entropy by toxic elimination via kidney system, skin, mucous membranes (genito-urinary, gastro-intestinal and respiratory mucosa), hepato-enteric and lymphatic elimination.
Systems’ informational endings my also be impaired by ionic current malfunction and chemical mediators (neurotransmitters, adrenalin) depletion. In more retractable diseases multiple communicating systems failure may reach refractory stage.